21 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
NON-WEIGHT BEARING CHILD ... RED FLAGS - In all ... cell disease Rheumatology ... #Peds #Pediatrics ... #Diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... • Scleroderma renal ... • Catastrophic APLS ... #differential #diagnosis ... #hematology #hemolysis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... , CML, AML, APML ... distinctive primary granules ... #Leukemia #Hematology ... #Oncology #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - PNH - APLS ... Decreased Support Of Dermal ... #Differential #Diagnosis ... #hematology #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... opacities • Diagnosis ... Anaphylaxis, Acute Renal ... unless severe APLS ... #hematology #oncology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... TMAs but (almost) all ... /o significant renal ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... hemolysis • Renal ... Anticardiolipin IgG > 40 GPL ... Erythematosus #diagnosis ... #rheumatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
cataracts, and renal ... of platelet α-granules ... #differential #diagnosis ... #hematology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... complications - Renal ... HenochSchonleinPurpura #HSP #Diagnosis ... #Rheumatology # ... Peds #Pediatrics
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Features: POEMS, AL ... Cryoglobulinemia Renal-centered ... #Differential #Diagnosis ... #hematology #oncology