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diagnosis overview pharmacology cardiology infectiousdiseases infective amikacin aminoglycosides antibiotic antifungal aorta aortic bacteria bcnie bloodculture causes clinical dalfopristin daptomycin echocardiogram
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Mechanism: Lipopeptide antibiotic ... MRSA bacteremia/endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Infective endocarditis - etiology and sources of infection. • Native and prosthetic valve endocarditis •
Infective endocarditis ... prosthetic valve endocarditis ... for TPN) and antibiotic ... #Infective #Endocarditis ... Bacteria #Etiology #Differential
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... for bacteremia/endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Flutycosine - Antibiotics Class Overview - Mechanism: 5-FC interferes with DNA and protein synthesis. Only
Flutycosine - Antibiotics ... candidal infections (endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Failure - Differential ... Treatment: • Antibiotic ... lines, osteo, endocarditis ... #Failure #Differential
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Endocarditis Summary ... Prosthetic Valve Endocarditis ... Marantic (NTBE) Differential ... • IV Antibiotics ... #Endocarditis
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Culture-Negative Infective Endocarditis ... Work-up of BCNIE relies ... Negative #Infective #Endocarditis ... #diagnosis #differential
Aortic Valve Endocarditis on POCUS Echocardiogram (PLAX) 50 yo female presents with fever & flu-like symptoms.
Aortic Valve Endocarditis ... prompted w/u for endocarditis ... PSLA view with subtle ... broad spectrum antibiotics ... #aorta #Valve #Endocarditis
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 Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... and Differential ... Treatment • IV antibiotics ... #Endocarditis ... #Differential #
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