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differential causes hyperkalemia algorithm nephrology high hypokalemia management symptoms treatment cardiology signs classification medications sideeffects syndrome antiarrhythmics classes inhibitors low
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
- Differential Diagnosis ... Transcellular Shift ... #Differential #Diagnosis ... Algorithm #causes #potassium ... #low #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
- Differential Diagnosis ... Transcellular Shift ... Transcellular shifts ... #Differential #Diagnosis ... nephrology #low #potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm • Increased Intake • Reduced Excretion (IV potassium with
- Differential Diagnosis ... Excretion (IV potassium ... Transcellular Shift ... #Differential #Diagnosis
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... adapt to excess potassium ... dysfunction is common #Diagnosis
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 Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... Differential #Causes #Diagnosis
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... the cell, serum potassium ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium ... #high #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium ... #Differential #Diagnosis
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