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hematology differential neurology algorithm oncology rheumatology pulmonary renal encephalopathy leukemia lupus sle summary thrombocytosis barre classification cll diarrhea erythematosus gastroenterology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... of chronic kidney ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... malignancies • Anemia ... Myelodysplastic syndrome ... #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... • Anterograde amnesia ... Chronic presentation ... Encephalopathy Treatment ... #neurology #diagnosis
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Evaluation of Chronic ... Causes of acute ... #Diarrhea #management ... #algorithm #workup ... #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... - Differential Diagnosis ... Cardio-pulmonary disease • Anemia ... • Chronic Infection ... Lambert-Eaton Myasthenic Syndrome
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... - Differential Diagnosis ... vasoconstriction syndrome ... Cerebral Hypoxia, Uremia ... #neurology
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