19 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... phenomenon (20%) Joints ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
, Fever, No muscle ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... • Rheumatic fever ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... acute rheumatic fever ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup #differential
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... Symptoms Alopecia, Fever ... Adenopathies, Lupus ... Erythematosus #SLE #Signs ... Symptoms #diagnosis #rheumatology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
ms after) the J point ... • De Winter syndrome ... V2 • Wellens sign ... pain • Wellens sign ... EKG #diagnosis #differential
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Pediatrics Patient - Differential ... Suggestive of: Rheum Fever ... migrans: • Target sign ... gabrieltalledop #dermatology ... arthritis #skin #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... erythematosus #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... #pain #Differential ... Diagnosis #MSK #rheumatology