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diagnosis symptoms hematology erythematosus hemolytic lupus rheumatology systemic workup aids anaplasma autoantibodies celiac chronic cll clues deficiency disease gastroenterology geography
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Autoimmune Hemolytic Anemias ... Alloimmune Hemolytic Anemias ... #Hemolytic #Anemias
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... paraesthesiae • Folate - Anaemia ... , neural tube defects ... Vitamin B12 - Anaemia ... #diagnosis #signs
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
scapularis • Infects ... within morulae Signs ... myalgias, shaking chills ... immature forms) • Anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis Algorithm ... suspected: • Signs ... Iron-deficiency anemia ... discernable cause • Signs ... microscopic colitis Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... genotypes): SS, SC, SE ... ARUPLabs #Hemolytic #Anemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Restrictive lung defect ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus #SLE ... erythematosus #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... (aPL) 30-45% Differential ... Lupusreference #SLE ... autoantibodies #signs
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... , anemia, febrile ... and coordination deficits ... #headache #signs ... symptoms #clues #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... • M > F • Affects ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Infections in HIV - Differential ... • CT: Halo sign ... you have HIV), Chills ... 100% of cases), anemia ... AIDS #pulmonary #differential
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