41 results
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
scapularis • Infects ... within morulae Signs ... myalgias, shaking chills ... • Rash is rare ... (< 10% cases),
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... RashDecisionz #Shawl #sign ... Dermatomyositis #Rash ... #Clinical #Photo
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... dullness, puddle sign ... incisional). 3) Signs ... Jcortesizaguirr #Ascites #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... defect (rare) Raynaud's ... erythematosus #signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... investigations depending on clinical ... context and signs ... #Injury #AKI #Workup
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... auricular papules Clinical ... anti-NXP2 Abs Lung
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical ... Alzheimer - 1st cause ... (parkinsonian signs ... Dementia - 2nd cause ... MNCD #Dementia #Differential
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical ... pathology #lesions #differential
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... - Differential ... Auspitz sign, Koebner's ... Papulosquamous #SkinRash #dermatology ... Diagnosis #Algorithm #causes