12 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
A1c Lowering Metformin ... + DPP4 • Janumet ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
• Biguanides (Metformin ... • Biguanides (Metformin ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Diabetes #DM2 #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side Effects ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... - Metformin - ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... • If Gl side effects ... #Prescribing #Dosing ... #CKD #pharmacology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... gastrointestinal (GI) adverse effects ... form and consider using ... medication #Metformin ... Indications #Titration #Pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... DM2 #diabetes #endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
Metformin: Biguanide ... Metformin is the ... point for side effects ... 2000 mg/day) and using ... #Pharmacology #
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
drugs include side effects ... Side effects include ... combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... DM2 #Diabetes #Endocrinology