26 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... -100): • Non-hemolytic ... Infections Macrocytic ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... (cell) volume (MCV ... acute blood loss, hemolysis ... (BM) ablative disorders ... Diagnosis #Workup #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia (sometimes) Macrocytic ... Unstable hemoglobin disorders ... IgM associated lymphoma ... , Malignant lymphoma ... differential #diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Polychromatic Macrocytes ... Bleed • Hemolysis ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... • Drugs Oval Macrocytes ... • Small Bowel Disorder ... #Macrocytic ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... • Bleeding • Hemolysis ... #Classification ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... , Auer rod • Lymphoid ... Pseudo Pelger-Huet, Macrocytic ... Proliferation • Lymphoid ... #hematology #Markers
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Differential Diagnosis Algorithm ... Malignant • Lymphoma ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
e.g. lupus, CLL, lymphoma ... cold agglutin disease ... lymphoproliferative disorders ... e.g. sickle cell disease ... differential #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes, MCV ... Anemia of Chronic Disease ... Non-lmmune #Anemia #Classification ... #Causes #Hematology