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diagnosis differential erythematosus obstetrics pregnancy sle systemic signs table ttphus anemia autoantibodies causes classification criteria disease eularacr extravascular hepatitis hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... coagulation (DIC) - HELLP ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Thrombocytopenia ... Syndrome and Acute ... (Hemolysis, Elevated ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... (Hemolysis, Elevated ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Syndrome (Hemolysis ... clinical features: Hemolysis ... , Thrombocytopenia ... obstetrics #hepatitis #comparison ... #AFLP
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Neurologic domain: Delirium ... pericarditis • Hematologic ... domain: Leukopenia, Thrombocytopenia ... , Autoimmune hemolysis ... Erythematosus #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... Lymphadenopathies 7% - Hemolytic ... autoantibodies #signs #symptoms ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
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