21 results
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... • Withdrawal ... symptoms - ... #Pathophysiology ... Diagnosis #Signs #Symptoms
Phenobarbital monotherapy algorithm for alcohol withdrawal

** EDIT - SEE UPDATED ALGORITHM HERE:
https://www.grepmed.com/images/4060/phenobarbital-monotherapy-withdrawal-management-algorithm-protocol-pulmcrit

-Phenobarbital monotherapy has numerous advantages
algorithm for alcohol withdrawal ... addition to alcohol withdrawal ... Alternative causes of delirium ... the underlying disorder ... Management #Alcohol #EtOH
Buprenorphine-Naloxone and treatment of withdrawal symptoms

Prerequisites for starting Suboxone in the ED:

1. Patient has an opioid
Buprenorphine-Naloxone and treatment ... of withdrawal symptoms ... an opioid use disorder ... Suboxone #Opioid #Withdrawal
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
-> potentially Delirium ... >2 days after EtOH ... • Delirium Tremens ... #Pathophysiology ... #EtOH
Updated phenobarbital alcohol withdrawal protocol

See old algorithm here: https://www.grepmed.com/images/1485/phenobarbital-monotherapy-withdrawal-management-algorithm-pulmcrit-protocol

The protocol was consequently modified as shown below,
phenobarbital alcohol withdrawal ... received sufficient treatment ... for alcohol withdrawal ... Any residual delirium ... Management #Alcohol #EtOH
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... mood - Primary treatment ... mood - Incr withdrawal ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager

Scoring Alcohol Withdrawal Syndrome (AWS):
 • PAWSS
 • CIWA-Ar
 •
Symptom Timeline ... Symptoms (6-36 ... vital signs • Delirium ... diaphoresis) Treatment ... #management #etoh
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... pattern of spread, B symptoms ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
musculoskeletal symptoms ... Psychiatric symptoms ... vasculitis Treatment ... weeks #Scurvy #Pathophysiology ... #AscorbicAcid #Pathophysiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder ... HIV dementia Pathophysiology ... • Depressive symptoms ... Treatment: • HAART ... treatment • Cognitive