43 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
100% Hepatic, 0% Renal ... 75% Hepatic, 25% Renal ... 20% Hepatic, 80% Renal ... NOAC #Metabolism #Pharmacology ... Clearance #oral #anticoagulation
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduction #Dose #Anticoagulation ... #Pharmacology # ... AFib #Renal #CKD
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Monitoring - Renal ... Resume #Oral #Anticoagulation ... Management #Table #Pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Rivaroxaban • Renal ... Bloodman #DOAC #anticoagulation ... #dosing #ckd #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Prophylaxis, VTE and Renal ... Dosing Renal ... Apixaban (25% renal ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
anticoagulant for treatment ... coagulopathy - LMWH • Renal ... decisionaid #vte #anticoagulation ... #pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... management #algorithm #pharmacology ... #treatment #medications ... #decisionaid #cardiology ... #hematology #warfarin
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
bleed risk on anticoagulation ... 1 A Abnormal renal ... liver function Renal ... (renal replacement ... AFib #Diagnosis #Hematology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... the first-line treatments ... #Pharmacology #Pathophysiology
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
patients with VTE treatment ... Fibrillation requiring anticoagulation ... patients with normal renal ... Rivaroxaban #Dosing #Pharmacology