43 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Special cases (e.g. renal ... #rheumatology # ... pharmacology #levels ... #lupus #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Irritable Bowel Syndrome (IBS) Treatment Options
Amitiza (Lubiprostone)
Antidepressants: Celexa, Wellbutrin, Prozac, Paxil, Nortriptyline, and Zoloft
Bentyl (Dicyclomine)
Creon
Ducolax
Imodium, Maalox,
Irritable Bowel Syndrome ... Nortriptyline, and Zoloft Bentyl ... irritable #bowel #syndrome ... #constipation #management ... #pharmacology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Associated - SLE ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus #SLE ... symptoms #diagnosis #rheumatology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
of Hepatorenal Syndrome ... pressure incr renal ... #HepatoRenal #Syndrome ... #Nephrology #Management ... #Pharmacology #
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Intravenous fluids • Renal ... #TumorLysis #Syndrome ... TLS #diagnosis #management ... #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... lymphadenopathy • Central ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology