29 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical Significance ... capillary leak syndrome ... • Schnitzler syndrome ... Cryoglobulinemia Renal-centered ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
gammopathy of renal ... significance (MGRS ... Capillary leak syndrome ... • Tumor lysis syndrome ... #AKI #Cancer #Oncology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... continue to have significant ... Myositis #diagnosis #rheumatology
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Peripheral and Central ... CENTRAL VERTIGO ... (Wallenberg's syndrome ... associated with significant ... Syndrome usually
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... tests in Behcet syndrome ... management #signs #symptoms ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Auer Rods Significant ... develop leukostasis syndrome ... translocation • Significant ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... Anaphylaxis, Acute Renal ... Differentiation #Syndrome ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... of Undetermined Significance ... of Undetermined Significance ... Exposure to heavy metal ... #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs #symptoms ... #diagnosis #rheumatology