11 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... ): • Acute infection ... malignancies • Anemia ... Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... disorders • Celiac ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... , deficiency anemia ... Vasculitides, IBD, Celiac ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... (AML) - CD13, CD33 ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Approach - MCV) ... kidney disease, Acute ... syndrome - Dr ... #diagnosis #causes ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
to Anemia - Differential ... Blood Loss • Acute ... #Classification ... #Approach #Differential ... #Causes #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... febrile neutrophilic dermatosis ... initiation • Differential ... #APML #diagnosis ... #management #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... - APLS • Acute ... Pigmented Purpuric Dermatosis ... #Diagnosis #hematology ... #nonpalpable #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... basophilia, and thrombocytosis ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis