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diagnosis rheumatology sle table dermatology vasculitis ana antinuclear comparison management types allergy autoantibodies hypersensitivity patterns reactions signs symptoms activation algorithm
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... #Antinuclear #Antibodies ... #diagnosis #differential
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #dermatology #Differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... SLE-Related Auto-Antibodies ... #Lupus #Erythematosus ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... permanent alopecia Differential ... lupus erythematosus ... #Lupus #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... pericarditis • Hematologic ... Highly specific antibodies ... #Lupus #Erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Evolution: Chronic disease ... #Systemic #Erythematosus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... #erythematosus #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... -15% If SLE is clinically ... #lupus #erythematosus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... Hypersensitivity #Types #Classification
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