13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Lupus Erythematosus ... (SLE) Clinical ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... #lupus #Systemic ... #Erythematosus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... /systemic sclerosis ... severe disease Treatment ... #Lupus #Erythematosus ... diagnosis #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... • Contact dermatitis ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and treatment can ... lupus erythematosus ... BEE #Syndromes #neurology ... #differential #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... months to years) Systemic ... Lupus Erythematosus ... life-threatening • Treatment ... #rheumatology #diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
- Diagnostic approach ... associated with systemic ... lupus erythematosus ... #Nephritis #diagnosis ... #nephrology #biopsy
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupus Erythematosus ... for 1 year of treatment ... #Systemic #Lupus ... #differential #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Focal Hand Neuromyotonia 

Focal neuromyotonia in SLE.  A 42 year old with a 10 year
neuromyotonia in SLE ... year history of Systemic ... lupus erythematosus ... was diagnosed. ... clinical #video #neurology