14 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin manifestations ... #Lupus #Erythematosus ... #SLE #Summary # ... diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Evolution: Chronic disease ... #lupus #Systemic ... #Summary #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #dermatology #oncology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... , Cutaneous mimickers ... #Systemic #Lupus ... #Erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Cerebrovascular Disease ... #Lupus #Erythematosus ... #SLE #CNS #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
as systemic lupus ... erythematosus, ... strong sign of cutaneous ... , and SLE) • Urinalysis ... #rheumatology #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • Autoimmune diseases ... : - 10% SLE or ... Henoch-Schönlein purpura) • Cutaneous ... lupus erythematosus