13 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Neutrophilic dermatosis ... dermatomyositis, SLE ... leukocytoclastic vasculitis ... #dermatology #oncology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
(10%) : SLE +++ ... #dermatology #semiology ... #signs #lesions ... #diagnosis #clinical ... #manifestations
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... lesions • Discoid ... lupus erythematosus ... #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
lesions • Mononeuritis ... such as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Leukocytoclastic vasculitis ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #hematology #rheumatology ... #nonpalpable #dermatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... lesions and plaques ... inflammation on skin ... Livedo Reticularis, Vasculitis ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... ) • Cutaneous Lesions ... MCC-small vessel vasculitis ... #management #signs
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... #dermatology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Paraproteinemias #Hematology ... #Oncology