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diagnosis differential hematology causes morphology bloodcell dehydrogenase elevated extravascular ferritin intravascular laboratory lactate ldh macrocytic mcv microcytic microscopy nomenclature normocytic
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... - Iron-deficiency ... , Thalassemia, Iron-deficiency ... , Pulmonary emboli ... #key #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... deficiency anemia ... elliptocytosis, Severe iron ... deficiency anemia ... #microscopy #atlas
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... Bleed • Hemolysis ... • Early Iron ... Deficiency # ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... elliptocytosis - RBC ... • PK deficiency ... anemia • ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... inflammation) • Iron ... , CKD • Hemolytic ... Spherocytosis, G6PD, PK, HbC ... #MCV #Algorithm
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Anemia - Differential ... extravascular) hemolysis ... athletic training, Pulmonary ... #Deficiency #Anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Red cell distribution ... acute blood loss, hemolysis ... erythropoietin (EPO), iron ... substrate (e.g. iron ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Artifact (redo ... CBC) Autonomous ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... of red blood cell ... anemia, PNH, immune ... - Iron deficiency ... Legionnaires disease • Pulmonary
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