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diagnosis differential hematology hemolytic extravascular intravascular morphology anemias bloodcell classification hodgkins key lymphoma management mcv microscopy nomenclature normocytic oncology red
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... : • Autoimmune ... Hemolytic Anemias ... Hemolytic Anemias ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... anemia • ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
spherocytosis, Autoimmune ... hemolytic anemia ... Agglutinate: Cold autoimmune ... hemolytic anemia ... #microscopy #atlas
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... • Intrinsic RBC ... Extravascular #Causes ... #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Hypochromic & microcytic RBCs ... idiopathic, malignancy, autoimmune ... #causes
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... spherocytosis, Hemolytic ... PD deficiency, Pulmonary ... #Morphology #Atlas
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... elliptocytosis, autoimmune ... #Anemia #Differential ... #workup #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... , CKD • Hemolytic ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... #MCV #Algorithm
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... platelets - WBC
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