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diagnosis hematology anemia bleeding bruising prolonged pt abnormal apml arterial deficiency dic differentiation disorders disseminated embolism extravascular ferritin hemolysis hemolytic
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... coagulation (DIC ... ) - HELLP syndrome ... #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... • Disseminated Intravascular ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... INR < 2.3 - APTT ... #causes #treatment ... #management #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Deficiency Anemia - Differential ... Diagnosis Algorithm ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... #ferritin #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... - Disseminated intravascular ... coagulation and ... other causes of ... #hematology #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... von Willebrand syndrome ... , disseminated intravascular ... discern these causes ... #Diagnosis #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
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