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diagnosis anemia mds algorithm aplastic apml arterial bleeding bruising coagulation dic differentiation disseminated embolism hemostasis key macrocytic macrocytosis mcv morphologic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Macrocytosis #elevatedMCV ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Myelodysplastic ... syndrome, Increased ... , Pulmonary emboli ... Hemolytic uremic syndrome ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - ... marrow) -dys- (abnormal ... #Syndrome #MDS ... #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... syndromes are a ... syndromes with ... blood count with differential ... #hematology #oncology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Hypothyroidism, Myelodysplastic ... syndrome - Dr ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... syndrome (MDS) ... #hematology #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... - Disseminated intravascular ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... Imaging: CXR- pulmonary ... Differentiation #Syndrome ... #hematology #oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... von Willebrand syndrome ... , disseminated intravascular ... discern these causes ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... thrombopoietin deficiency ... #treatment #management ... #hematology
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