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oncology syndrome chronic classification cll differential encephalopathy leukemia lymphocytic mds myelodysplastic workup alkaline alp apml arteritis coagulation comparison crisis dic
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Script Signs and symptoms ... #Anemia #diagnosis ... #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #hematology #diagnosis ... #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... marrow failure with anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... Avoid meds that ... #Management #treatment ... #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... #causes #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... Renal Failure Treatment ... #management #hematology
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