31 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... • Immunologic Workup ... life-threatening • Treatment
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... 69% - Malar rash ... Lymphadenopathies 7% - Hemolytic ... #Systemic #Lupus ... autoantibodies #signs
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... can present with rash ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... #comparison #table ... #rheumatology # ... diagnosis #management
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... genotypes): SS, SC, SE ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... and systemic toxicity ... differential diagnosis ... rashes but without signs ... #Diagnosis #Dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment ... #Algorithm #hematology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... (SLE) - Typical ... Signs/Symptoms ... , Fever, Malar rash ... #diagnosis #rheumatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... The signs and symptoms ... , but without treatment ... #Diagnosis #Clinical ... #Photo #Dermatology