23 results
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
Hepatopulmonary Syndrome (HPS ... ) HPS-differential ... Pulmonary vasculature ... Alveolar-arterial oxygen gradient ... #hepatology #pulmonary
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... • Young age ... Asymptomatic, Age ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... - Bimodal Age ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
DOACs thereby leading ... metabolization leading ... whereas edoxaban has ... #Chemotherapy #Oncology ... #Hematology #Interactions
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... pressure and the diastolic ... Blood Pressure - Diastolic ... : • Advanced age-arteriosclerosis ... Infarction • Pulmonary
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN) RPGN has ... three primary pathophysiologic ... causes differentiated ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
that coagulation has ... D-dimer has been ... , which can cause ... Ddimer #dimer #pathophysiology ... #hematology #differential
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... Risk factors: Age ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... of gestational age ... Liver #Pregnancy #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... uremic syndrome (HUS ... lactam antibiotics are ... #differential # ... diagnosis #hematology