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Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
) -> Increased coagulation ... decreased anti-coagulation ... retinal edema caused ... ischemia results in disc ... -> Pale Optic Disc
Common causes of sciatica. Disc herniation is the commonest cause. Spondylolisthesis can cause impingement #Anatomy #Pathophys
Common causes of ... Disc herniation ... the commonest cause ... Spondylolisthesis can cause
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... Treat primary cause ... • Correct coagulation ... #diagnosis #causes
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC) #Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Intravascular Coagulation ... (DIC) #Diagnosis ... #TTP #DIC #Comparison
Pathological Optic Disc Cupping Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5). Thinning of optic disc
Pathological Optic Disc ... Note cup-to-disc ... so that optic disc ... Usual cause is glaucoma ... Glaucoma causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... disorders CAUSES ... Kasabach-Merritt syndrome Coagulation ... Defects: • DIC
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation ... (DIC) INFLAMMATORY ... MAHA: TTP, HUS, DIC
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... HIT, ITP/HUS), Coagulation ... defects (DIC, warfarin ... nonpalpable #palpable #Causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Vasculitis Coagulation ... deficiencies Coagulation ... Intravascular Coagulation ... Diagnosis #Algorithm #Causes
4 T’s Mnemonic for Causes of Post-Partum Hemorrhage (PPH) Tone (70%): - Uterine Atony - Tx: Massage,
s Mnemonic for Causes ... Coagulopathies, DIC ... - Tx: Replace coagulation
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