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Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... IBD • RA • SLE ... Psoriatic arthritis Discoid ... skin lesions • Discoid ... erythematosus • SLE
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Malar Rash D Discoid ... #IMDAMNSHARP #sle
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... follicular plugging -> Discoid ... Phenomenon #Lupus #SLE
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Nummular Dermatits (Discoid ... - Coin shaped (discoid
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Diagnosis and Management ... are evocative of SLE ... Usual therapeutic management ... Erythematosus #Diagnosis #Management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Subacute cutaneous or discoid ... Classification #Criteria #SLE
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
manifestations • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... #rheumatology #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Erythematosus (SLE ... are evocative of SLE ... Usual therapeutic management ... rheumatology #diagnosis #management
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... patients with typical SLE
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... RA, Sjögren, SLE ... Bronchiectasis #diagnosis #management
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