20 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Primary Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology ... #comparison
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... Environmental Risk ... polish Epigentics Risk ... methylation Genetic Risk ... #hepatology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding risk ... #Diagnosis #Hematology ... CHADS2VASc #HASBLED #Comparison ... #Score #Risk #Stroke
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
) Mayo Clinic Risk ... CBC, complete blood ... diagnosis #management #hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
scores for stroke risk ... and bleed risk ... dL) 1 Liver (cirrhosis ... #Score #Risk #Stroke ... AFib #Diagnosis #Hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
are not a major risk ... cancer screening, CBC ... Hypercoagulable #Workup #hematology ... diagnosis #algorithm #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... transfused patients • Risk ... Transfusion #Reactions #hematology ... #diagnosis #comparison
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
CIRRHOSIS - ... Progression to cirrhosis ... decompensated cirrhosis ... are at increased risk ... management #summary #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Attempt if high risk ... QD until normal WBC ... fluid overload, PCC ... diagnosis #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... cardiovascular risk ... Venous #Arterial #pathophysiology ... #hematology #differential