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differential hematology coagulation algorithm aptt bleeding prolonged arterial classification dermatology embolism hemoptysis hemostasis intravascular management pathophysiology pediatrics peds petechiae petechial
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... • Steroids • Vasculitis ... Deficiency • Disseminated ... #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... deficiency - Abnormal ... Meningococcemia - Disseminated ... fulminans - DIC
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... ABNORMAL PT/ ... discern these causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... hemorrhage • Disseminated ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... Fibrinogen: ↓ • PT ... #Disseminated # ... #Coagulation #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Dissection • Aneurysm ... thrombocytopenia - Disseminated ... coagulation and other causes ... 19 - PNH - Vasculitis
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Autoimmune: ANCA-Assoc vasculitis ... AVM, Thoracic aortic ... aneurysm Misc ... Coagulopathy: DIC ... #pulmonary #causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Thrombosis and arterial aneurysms ... aneurysm • Medium ... #rheumatology #
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... (disseminated intravascular ... infections - Vasculitis ... pediatrics #diagnosis
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