35 results
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Expression → ↑ VLDL Production ... Secretion → ↑ LDL Production ... sequestration #pathophysiology ... #pharmacology #
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder Dislocation ... Overhead throwing => Abduction ... Anterior Shoulder Dislocation ... x-ray view -> Dislocation ... #orthopedics #pathophysiology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... the first-line treatments ... #Pharmacology #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
may be seen in association ... Decreased tear production ... Decreased saliva production ... Decreased sebum production ... Sjogrens #Syndrome #Pathophysiology
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Combinations of Non-Pharmacologic ... Reduction in Utilization ... Medication Assisted Treatment ... (MAT) and Harm Reduction
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Excessive heat production ... transfusion • Allergic reaction ... brain injury By Association
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... 2,3-DPG and a reduction ... shifts the oxygen dissociation ... the hemoglobin dissociation ... respiratory #hypoxia #pathophysiology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Severe adverse drug reaction ... extensive skin rash in association ... Exanthematous drug reaction ... disease: symptomatic treatment
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Fracture • Hip dislocation ... Decr ROM in hip abduction ... Trendelenburg #Gait #pathophysiology