17 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their ... on the Kidney - Pathophysiology ... hyporenin hypoaldo, hyperkalemic ... @kdjhaveri #NSAIDS ... KidneyDisease #nephrology
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... Remember that NSAIDs ... kidney function, NSAID ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Renin Release: NSAIDs ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... Impaired #Potassium #Renal
Renal Tubular Disorders

 • Distal Renal Tubular Acidosis (Type 1)
 • Proximal Renal Tubular Acidosis (Type
Renal Tubular Disorders ... • Distal Renal ... Acidosis (Type 2) • Hyperkalemic ... Acidosis #Types #pathophysiology ... #nephrology #diagnosis
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
diuretics • NSAIDs ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
diuretics • NSAIDs ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
3 months Pre-Renal ... Atheroemboli • Renal ... eosinophiluria) • Drugs (NSAlDs ... Hyperoxaluria • Hypercalcemia ... KidneyDisease #Nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
AKI) What to ask ... Nephrotoxins (NSAlDs ... protein/Cr - Renal ... - 45% - Pre-renal ... AcuteKidneyInjury #AKI #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... Excretion: - Renal ... tourniquet / IVF line draw ... 15 suggests ↓ renal ... Treatment #potassium #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
heart failure, neurologic ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... Pheochromocytoma • Toxic: NSAlDs ... Neurologic disorders