39 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
disease by organ system ... are indicated in bold ... Disease #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and duration of symptoms ... angioedema Other symptoms ... #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
, C3d ( +/- ) Cold ... ) Paroxysmal cold ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology ... #diagnosis
Indolent Systemic Mastocytosis (ISM)

 • Introduction and Diagnosis
 • Diagnostic Algorithm and Risk Stratification
 • Symptoms
Indolent Systemic ... Stratification • Symptoms ... and Symptom Management ... @ZhuoerXie #Systemic ... #SM #Indolent #hematology
Molluscum Contagiosum 
Clinical 
 • Most common in school-age children 
 • Transmitted by direct contact
• Painless, no systemic ... symptoms • Typically ... extremities • Spares ... #Contagiosum #Diagnosis ... Clinical #Management #Dermatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... BostonChiefs #Warm #Cold ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
symptoms - most ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology ... #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA, Cold ... Laboratory Tests ... #Differential #Diagnosis ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... practices that could ... K), H. pylori test ... (GI symptoms/endemic ... Causes #Workup #hematology