11 results
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... Interactions With ... Licorice - Causes hypokalemia ... effects #DrugDrug #Interactions ... supplementals #herbal #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Cyclosporine) • Increased ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... Increased potassium ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential Diagnosis ... Algorithm Increased ... #Algorithm #causes ... potassium #low #pathophysiology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Algorithm Decreased ... Hypokalemic distal RTA Increased ... Serum K = Hyperkalemic ... nephropathy - Drugs ... Jain via UNC IM
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
g once daily Increase ... from other oral drugs ... this from other drugs ... after) to avoid interactions ... #Pharmacology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of ... Malignancy - Pathophysiology ... dihydroxyvitamin D - Increased ... #Differential #Diagnosis ... #algorithm
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
- Differential Diagnosis ... Algorithm Primary ... Over-production • Increased ... Sarcoidosis • Hypercalcemia ... #Differential #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential Diagnosis ... Algorithm Endocrine ... Liver Failure • Hypercalcemia ... Myasthenia Gravis Pharmacologic ... #Algorithm #causes
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Hydromorphone (Dilaudid) - Increased ... A dissociative drug ... metabolism (med interactions ... No pharmacologic ... #CriticalCare #diagnosis