14 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... Increased potassium ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
, which causes increased ... RAAS inhibiting drug ... avoid harmful hyperkalemia ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - Hyperkalemia ( ... , in states of hypokalemia ... #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
g once daily Increase ... from other oral drugs ... this from other drugs ... after) to avoid interactions ... #Pharmacology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential Diagnosis ... #Differential #Diagnosis ... Algorithm #causes #potassium ... #low #pathophysiology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... Interactions With ... Licorice - Causes hypokalemia ... effects #DrugDrug #Interactions ... supplementals #herbal #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... hypoperfusion Increased ... #causes #potassium
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
- Differential Diagnosis ... Hypokalemic distal RTA Increased ... Serum K = Hyperkalemic ... nephropathy - Drugs ... Jain via UNC IM