371 results
Immune Checkpoint Inhibitors

PD-1 inhibitors
 - Nivolumab
 - Pembrolizumab
CTLA-4 inhibitors
 - Ipilimumab
 - Tremelimumab
PD-L1 inhibitors
 - Atezolizumab
Immune Checkpoint ... Inhibitors PD ... -1 inhibitors ... Atezolizumab - Durvalumab ... #Immune #Checkpoint
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
Checkpoint inhibitors ... Breast cancer • Durvalumab ... cell cancer #Checkpoint ... #inhibitors #indications
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
Table Aspirin - Inhibits ... in a-fib P2Y12 Inhibitors ... ticagrelor) - Inhibits ... , abciximab) - Inhibits ... (and PDE3 inhibition
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... Angiotensin-converting enzyme (ACE) inhibitors ... of aldosterone inhibition ... • Calcineurin Inhibitors
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Check point inhibitors ... of check point inhibitors ... by stopping the checkpoint ... inhibitor and inducing
HIV HAART Medications - Classification by Names and Mechanism - Updated 01/2021
 - NRTIs
 - NNRTIs
NNRTIs - Protease Inhibitors ... - Integrase Inhibitors ... Antagonist - Fusion Inhibitor ... - Attachment Inhibitor
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Between P2Y12 Inhibitors ... Oral P2Y12 inhibitors ... Switching P2Y12 inhibitors ... between P2Y12 inhibitors ... and Oral P2Y12 Inhibitors
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
steroids, calcineurin inhibitor ... anti-metabolite - Immune Checkpoint ... Inhibitors: cessation
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
are both CYP3A4 INHIBITORS ... actually a protease inhibitor ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... because of the CYP inhibition
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Biguanides - Inhibit ... CARB ABSORPTION INHIBITOR ... alpha-glucosidase inhibitor ... SGLT-2 - Inhibit ... agonists - Inhibit