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differential management syndrome anemia coagulation treatment disorders prolonged workup aptt classification elevatedmcv erythematosus gca hepatology lupus macrocytic macrocytosis microcytic nephrology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... (INR), Normal PTT ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... #Algorithm #Causes ... #Hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... • Secondary (e.g ... #Algorithm #Causes ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Algorithm Infectious ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Algorithm #Causes ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... to one factor e.g ... e.g. heparin ... #Causes #diagnosis ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal ... Increased Requirement (e.g ... #Algorithm #Causes ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Rare • Drugs (e.g ... #Algorithm #Causes ... #Hematology
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