25 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... (+) ↑ WBC ... o Other bcr-able ... #hematology #Markers ... #Differential #
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
• Thrombus (e.g ... Myeloproliferative disorders ... (eg. polycythemia ... Disease • Sickle Cell ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
. lupus, CLL, lymphoma ... lymphoproliferative disorders ... • Intrinsic RBC ... . sickle cell disease ... #diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... (BM) ablative disorders ... of substrate (e.g ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... • Secondary (e.g ... - Sickle Cells, ... Target Cells ... Algorithm #Causes #Hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Hematopoietic stem cell ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Solid Tumour (e.g ... • Metabolic disorders ... pancytopenia, blast cells ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... function test, ANA (e.g ... #Differential # ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Increased Requirement (e.g ... • Small Bowel Disorder ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology