38 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... permeability Diagnosis ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Special cases (e.g ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... 40, F:M 9:1 • Clinical ... Erythematosus #Diagnosis ... #rheumatology
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Internet Book of Critical ... Vasopressors #Properties #Table ... #Pharmacology # ... Effect #Management
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
prior resistance. e.g ... ESBL, KPC, VRE. etc ... ampicillin #management ... #antibiogram #pharmacology ... #table #sensitivities
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... -15% If SLE is clinically ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
rupture, VSD, etc ... vasoactive drug pharmacology ... #inopressors #diagnosis ... #management #comparison ... #table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology