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diagnosis differential management causes transfusion algorithm anemia coagulation hemolysis intravascular product atlas bloodbank bloodcell compatibility deficiencies deficiency disorders disseminated elevatedmcv
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
ABO Blood Types ... Compatibility Table ... rishikumarmd #ABO ... Compatibility #Table ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... 2) External (RBC ... AIHA, Transfusion reactions ... - Peripheral Blood ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation (DIC ... Other: Transfusion reaction ... - Transfusion reaction ... • Intrinsic RBC ... differential #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... antigens (often ABO ... pain, dark urine, DIC ... haptoglobin, ↑LDH, etc ... diagnosis #management #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... disease, McLeod blood ... Liver disease, Etc ... differential #diagnosis #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... Post-partum • Acute DIC ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Transfusions: Cellular blood ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Fe/TlBC, MCV/RBC ... Iron Deficiency (Eg ... Causes: Chronic Blood ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia) or ABO ... incompatible blood ... + Bleeding Treatment ... hydration • RBC ... #management #hematology
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