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diagnosis management differential algorithm reactions rheumatology anemia comparison intravascular oncology product atlas basics bloodbank cerebritis coagulation cryofibrinogenemia disseminated elevatedmcv eosinophil
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Immunodeficiency Disorder ... , etc ... HLA-selected products (e.g ... #Hematology #BloodBank
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... , Seizure disorders ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... lymphoproliferative disorders ... Extravascular #Causes ... differential #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Peripheral blood ... • Screen for secondary ... glucocorticoid treatment ... Differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... transfusion • ... Thromboembolism (7%) • CNS ... Treat primary cause ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... pain, dark urine, DIC ... haptoglobin, ↑LDH, etc ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... without other cause ... : 33% • Treatment ... #Reactions #hematology ... diagnosis #comparison #table
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... pain, dark urine, DIC ... haptoglobin, ↑LDH, etc ... Causes purpura & ... diagnosis #management #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Blood Loss, Occult ... 18% • Anemia Secondary ... HgbE, HgbC, etc. ... #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... , eg, cyclic neutropenia ... drug reactions - Secondary ... including white blood ... #hematology
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