39 results
diagnosis management differential algorithm anemia syndrome blood workup leukemia chronic elevatedmcv lymphocytic macrocytic macrocytosis mds microcytic myelodysplastic product reactions thrombocytosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
• Lymphoid (CLL ... - bcr-able (+) ... ↑ WBC ... o Other bcr-able ... #hematology #Markers
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... • Rheumatic disorders ... effect following treatment ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Hematopoietic stem cell ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... not required in all ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... • Intrinsic RBC ... differential #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... • Thrombus (e.g ... Myeloproliferative disorders ... Disease • Sickle Cell ... #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... (BM) ablative disorders ... of substrate (e.g ... Diagnosis #Workup #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Fe/TlBC, MCV/RBC ... Causes: Chronic ... HgbE, HgbC, etc. ... #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
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