47 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... , McLeod blood group ... , Etc. ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Electrolytes: Wilson's disease ... - Peripheral Blood ... Differential #Diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Neutrophils - Low RBC ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... - Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
- Fe/TlBC, MCV/RBC ... Iron Deficiency (Eg ... Causes: Chronic Blood ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Myelodysplastic syndrome ... coagulopathy (DIC) #RBC ... #differential #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... hemolytic anemia (e.g ... cells: Sickle cell disease ... Smear #Analysis #hematology ... interpretation #clinical
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... cold agglutin disease ... • Intrinsic RBC ... differential #diagnosis #hematology