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management diagnosis hemophagocytic hlh lymphohistiocytosis transfusion blood bloodbank differential drug emergency erythroderma hemeonc indications irradiated irradiation leukostasis lysis rashes rbc
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma DRESS - Onset:
Drug Rashes - Comparison ... exfoliation #Febrile ... #Drug #Rashes #Comparison ... #TABLE #DRESS # ... #Dermatology #Emergency
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Systemic Symptoms (DRESS ... ) Syndrome Treatment ... cyclosporine, IVIG etc ... #Syndrome #Treatment ... #Management #dermatology
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... SJS/TEN DRESS ... #Syndrome #SJS ... #TEN #comparison ... #table #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... : - If febrile ... Low calcium • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... four months of age ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 33% • Treatment ... Risk factors: Age ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... < 3 months of age ... acute or subacute febrile ... • Bicytopenia Treatment ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... hyperinflammatory syndrome ... search for and treatment ... Treatment Approach ... Diagnosis #Management #Hematology
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