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management algorithm syndrome systemic anemia classification disease disorders erythematosus hemolysis hemolytic lupus sclerosis sle vasculitis workup agglutinin als amyotrophic apml
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... Signs and Symptoms ... Hemolytic #Anemia #hematology ... #diagnosis #signs ... #symptoms
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Cold AIHA • PCH ... Prosthetic heart valves ... #Diagnosis #Algorithm ... #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
(aPL) 30-45% Differential ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
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