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management syndrome aids barre cns cord guillain spinal spinalcord algorithm als amyotrophic apml autoimmune caudaequina causes classification cmv cytomegalovirus differentiation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... cells per μL • Diagnosis ... #differential # ... diagnosis #AIDS
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
lumbar spine • MCC ... spine L1-L5 Symptoms ... Diagnosis: • ... cord infarct • HIV ... #neurology
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
CMV infection: virus ... PCR and CMV pp65 ... 50 or less: • Neurologic ... #differential # ... signs #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Diagnosis Framework ... Lower roots -> Cauda ... Infections: - ... HIV, CMV, HTLV ... #neurology #differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
immunodeficiency virus (HIV ... than one after symptom ... the underlying pathophysiology ... nerve roots and cauda ... #management #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... : HSV 1): • Herpes ... Coltivirus Symptoms ... influenzae Symptoms ... diagnosis #neurology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
cryoglobulinemia, post-infectious ... autoAb against type IV ... staining on IF • No EM ... Classification #Differential ... #Diagnosis #Nephrology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... Campylobacter jejuni - HIV ... nerve roots and cauda ... management #treatment #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Infarction - Infection ... syphilis, and HIV ... involvement Cauda ... syndromes #lesions #differential ... #diagnosis #neurology
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