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hepatology lfts algorithm hepatitis injury abnormal aflp causes chemistry cholestatic disease elevated elevation enzymes extravascular functiontest hellp hepatocellular icp interpretation
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... Cold AIHA • PCH ... Prosthetic heart valves ... #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... for Transaminitis ... #Algorithm #diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Diagnosis #hematology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... ) vs Indirect (Hemolytic ... ALP ≥ 2x ULN R Value ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 2-5x normal - Hemolysis ... #LFTs #transaminitis ... #differential # ... diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... injury #hepatitis #differential ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
HELLP Syndrome (Hemolysis ... clinical features: Hemolysis ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp #
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