17 results
diagnosis algorithm hematology causes anemia hemolysis hemolytic hepatitis injury liver extravascular intravascular rheumatology transaminitis treatment abnormal acute agglutinin aiha cold
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... • AIH • A1AT ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... , PCH, Evans Syndrome
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... 15X ULN - Drugs ... Hep, Drugs, Infection ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... • Alloimmune ... • PCH ... • PNH • Drug-induced ... Prosthetic heart valves
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... , Recreational Drugs ... Other: NAFLD, Autoimmune ... Liver #Injury #Differential ... Acute #algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... >1.5, and both values ... suspect drug within ... Hepatitis #Diagnosis #Hepatology ... #AIH
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... esp if severe disease ... , Splenectomy, MMF ... Treatment #management ... #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
valproate, azoles), Drugs ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(AIHA) "Warm" ( ... (AIHA)"Cold" (usually ... infection) - Drugs ... Extravascular #Causes #differential ... #diagnosis #hematology
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