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algorithm liver hematology management transaminitis acidosis chemistry cholestatic classification dili drug elevation embolism extravascular gastroenterology hemolysis hepatitis hepatocellular hyperkalemia idiosyncratic
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... • R value = (ALT ... #differential # ... hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
(DILI) DILI Types ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Diagnosis Framework ... Vasculitis • Injury ... #differential # ... diagnosis #vascular
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... elliptocytosis - RBC Enzyme ... Prosthetic heart valves ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... Source of Liver Enzyme ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... liver or renal injury ... ’s • Reduced Arterial ... #Diagnosis #causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum ... Source of Liver Enzyme ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... - ↓ Effective arterial ... Aldosterone, RTA Type ... only if no clear cause ... Elimination (see Table
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