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algorithm bruising thrombocytopenia bleeding chronic elevatedmcv fatigue hemolysis hemolytic hemorrhage macrocytic macrocytosis naildisorders neutropenia obgyn peds postpartum pph purpura secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... (usually IgG) (e.g ... #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Toxic Damage (e.g ... Displacement (e.g ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Diagnosis Algorithm ... TTP) • HELLP syndrome ... • Disseminated intravascular ... #Diagnosis #Algorithm ... #Causes #Obstetrics
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Diagnosis Algorithm ... Panhypopituitarism Treatment ... #Diagnosis #Algorithm ... #endocrinology ... #causes #pediatrics
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Rare • Drugs (e.g ... • Disseminated Intravascular ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Increased Requirement (e.g ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g ... #Diagnosis #Algorithm
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(disseminated intravascular ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... #diagnosis #differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... halt nail growth (e.g ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
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